China-WHO release new joint pneumonia investigation report Bats appear to be hosts without significant genetic mutations
China CCTV News: This morning (29th), the China-World Health Organization released a joint inspection report on new coronavirus pneumonia. The report pointed out that bioinformatics analysis showed that the new coronavirus has the closest genome-to-genome relationship with the SARS-like coronavirus strain carried by bats, with a homology of 96%. Bats appear to be hosts of the virus, but intermediate hosts have not been identified. A consensus comparison of the entire genome sequence of the virus showed no significant genetic mutations in the virus.
Regarding the mode of transmission, the report states that neo-coronary pneumonia is transmitted through droplets and close contact without protection. There are no reports of airborne neonatal pneumonia, and based on available evidence, airborne transmission is not considered to be the primary mode of transmission. However, there may be a possibility of airborne transmission in a medical institution due to aerosols generated by medical procedures. Fecal detoxification has been confirmed in some patients, but based on available evidence, fecal-oral transmission does not appear to be the main mode of transmission of neo-coronary pneumonia. In China, the interpersonal transmission of new crown pneumonia occurs mainly in the family.
The report states that between 1% and 5% of close contacts were later laboratory-diagnosed as cases of new coronary pneumonia. China has taken resolute and decisive measures to identify and track cases of new coronary pneumonia and close contacts. For example, Wuhan has more than 1,800 epidemiological investigation teams, with at least five in each group, tracking thousands of close contacts daily. It is through hard work that the vast majority of identified close contacts have been traced and completed medical observations.
Reports indicate that patients with neocoronary pneumonia usually develop mild respiratory symptoms and fever on average 5-6 days after infection. Most patients infected with the new corona pneumonia virus are mild and can be cured. About 80% of laboratory-confirmed cases are mild and general, 13.8% are severe, and 6.1% are critically ill.
Asymptomatic infections have been reported, but most asymptomatic cases at the time of reporting subsequently develop symptoms. The proportion of truly asymptomatic infections is unknown, but is relatively rare and not a major driver of transmission.
Severe people at high risk of death and death are those over 60 years of age and those with underlying diseases. Childhood cases appear to be rare and mild, with cases under 19 accounting for approximately 2.4% of total reported cases. Very few cases under the age of 19 have developed severe or critical illness.
In China, the crude case fatality rate is higher in the early stages of the outbreak; as time goes on, the crude case fatality rate of cases that fell after February 1 dropped to 0.7%. The case fatality rate increases with age, with the highest case fatality rate over the age of 80 (21.9%). Case fatality rates are higher in men than in women. The mortality rate of patients without comorbidities was 1.4%, and the mortality rate of patients with comorbidities increased significantly.
Regarding the mode of transmission, the report states that neo-coronary pneumonia is transmitted through droplets and close contact without protection. There are no reports of airborne neonatal pneumonia, and based on available evidence, airborne transmission is not considered to be the primary mode of transmission. However, there may be a possibility of airborne transmission in a medical institution due to aerosols generated by medical procedures. Fecal detoxification has been confirmed in some patients, but based on available evidence, fecal-oral transmission does not appear to be the main mode of transmission of neo-coronary pneumonia. In China, the interpersonal transmission of new crown pneumonia occurs mainly in the family.
The report states that between 1% and 5% of close contacts were later laboratory-diagnosed as cases of new coronary pneumonia. China has taken resolute and decisive measures to identify and track cases of new coronary pneumonia and close contacts. For example, Wuhan has more than 1,800 epidemiological investigation teams, with at least five in each group, tracking thousands of close contacts daily. It is through hard work that the vast majority of identified close contacts have been traced and completed medical observations.
Reports indicate that patients with neocoronary pneumonia usually develop mild respiratory symptoms and fever on average 5-6 days after infection. Most patients infected with the new corona pneumonia virus are mild and can be cured. About 80% of laboratory-confirmed cases are mild and general, 13.8% are severe, and 6.1% are critically ill.
Asymptomatic infections have been reported, but most asymptomatic cases at the time of reporting subsequently develop symptoms. The proportion of truly asymptomatic infections is unknown, but is relatively rare and not a major driver of transmission.
Severe people at high risk of death and death are those over 60 years of age and those with underlying diseases. Childhood cases appear to be rare and mild, with cases under 19 accounting for approximately 2.4% of total reported cases. Very few cases under the age of 19 have developed severe or critical illness.
In China, the crude case fatality rate is higher in the early stages of the outbreak; as time goes on, the crude case fatality rate of cases that fell after February 1 dropped to 0.7%. The case fatality rate increases with age, with the highest case fatality rate over the age of 80 (21.9%). Case fatality rates are higher in men than in women. The mortality rate of patients without comorbidities was 1.4%, and the mortality rate of patients with comorbidities increased significantly.
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